Image Source: Medpace.com
A recent study outlines a way to tell tissue-resident macrophages apart from infiltrating macrophages. By surgically joining a mouse to another mouse whose macrophages have been bound to green fluorescent tracers, it becomes possible to distinguish the tissue-resident macrophages from the green fluorescent infiltrating macrophages when both mice are injured. This new insight could pave the way for scientists to better understand the role of tissue-resident macrophages on muscular dystrophy, which could help improve therapies for DMD. They also discovered the potential role of resident macrophages on beneficial tissue muscle metabolism.