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|Crawling C. elegans hermaphrodite worm (Photo credit: Wikipedia)|
Humans possess the Nrf2 gene which is similar in nature and function to the SKN-1 gene and therefore, Dr. Curran is confident that his findings will eventually be effective in humans as well. Luckily for him, the Nrf2 gene has been well characterized in humans and the Nrf2 protein produced by the gene is involved in the damage repair machinery of the cells. The gene has also been studied excessively, since increased activity of the gene has been linked with cancers.
Pang, S., Lynn, D., Lo, J., Paek, J., & Curran, S. (2014). SKN-1 and Nrf2 couples proline catabolism with lipid metabolism during nutrient deprivation Nature Communications, 5 DOI: 10.1038/ncomms6048